Alternative Test Methods: Validation and Regulatory Status
- Acute Aquatic Toxicity
- Acute Mammalian Oral Toxicity
- Acute Mammalian Inhalation Toxicity
- Acute Mammalian Skin Toxicity
- Biologics (non-vaccine)
- Carcinogenicity
- Chronic/Repeated Dose Toxicity
| Conventional test method | Alternative Test Method | Infor- mation Last Updated | ||||
|---|---|---|---|---|---|---|
| Name & Description | Validation Status | Regulatory Status | Effect or Potential Effect on Animal Use | |||
| Chronic/Repeated Dose Toxicity | ||||||
Chronic Toxicity Study, second species, for pesticides (OECD TG 452) |
Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents Description and references |
EU: Endorsed as a valid strategy by ECVAM (2006) |
OECD: TG 409 (1998) US: Accepted by EPA (2007) |
Refinement |
April 2009 | |
Repeated Dose 28-day Oral Toxicity Study in Rodents AND |
Combined Repeated Dose Toxicity Study with the Reproduction/ Developmental Toxicity Screening Test
|
No information |
OECD: TG 422 (1996) |
Reduction |
April 2009 | |
List of Abbreviations
© 2009 CCAC, All Rights Reserved