Alternative Test Methods: Validation and Regulatory Status

Conventional test method Alternative Test Method Infor- mation Last Updated
Name & Description Validation Status Regulatory Status Effect or Potential Effect on Animal Use
Skin Penetration

Skin Absorption: In Vivo Method (OECD TG 427)

Skin Absorption: In Vitro Method
Description and references

No information

OECD: TG 428 (2004)

Replacement
(when using skin from human donors undergoing surgery)

OR

Reduction
(when using skin from animals)

 April 2009

List of Abbreviations