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Reduction Alternatives
Data sharing strategies
Data sharing strategies contribute to reduction by decreasing the total number of experiments that are undertaken
and assisting investigators to avoid duplication. In academic research, data is shared through publication in
peer-reviewed journals and at conferences. In non-academic research environments (e.g., industry), data is often
considered proprietary and not shared publicly. However, several initiatives involving the sharing of proprietary
data have been successfully undertaken by members of industry:
- Broadhead C., Betton G., Combes R., Damment S., Everett D., Garner C., Godsafe Z., Healing G., Heywood R.,
Jennings M., Lumley C., Oliver G., Smith D., Straughan D., Topham J., Wallis R., Wilson S. & Buckley P. (2000)
Prospects for reducing and refining the use of dogs in regulatory toxicity testing of pharmaceuticals.
Experimental Toxicology 19:440-447.
- Chapman K. & Robinson S. (2007) Challenging the regulatory requirement for acute toxicity studies in the
development of new medicines: A workshop report. NC3Rs.
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